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The article says gastrointestinal effects including nausea, constipation, and reduced appetite are most common in the first two to three weeks and typically diminish by week four
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Are GLP-1 medications like Ozempic suitable for long-term weight loss
These findings confirm that while the GLP-1 RAs do not materially increase rare adverse events such as pancreatitis and severe hypoglycaemia, gastrointestinal side effects represent a predictable and clinically relevant class effect that often limits tolerability
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