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doi: 10.1038/s41598-022-15010-2 49 CollinsS
In February 2025, the EMAs medicines committee issued a positive opinion on Krystal Biotechs Vyjuvek (beremagene geperpavec), the first topical gene therapy to treat wounds in patients affected by the ultra-rare but serious genetic blistering disease dystrophic epidermolysis bullosa (DEB)
Exclusion criteria included combination therapy, insulin as first-line treatment, and diabetes secondary to other causes
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The choice to use retatrutide should be informed by accurate information, personal medical circumstances, financial considerations, and individual risk tolerance
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