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In db/db mice, CK treatment increases secondary BAs, such as lithocholic acid (LCA) and deoxycholic acid (DCA) through changes in the gut microbiota, especially the Ruminococcaceae family, and up-regulation of cytochrome P450 family 7 subfamily B member 1 ( Cyp7b1 ) and cytochrome P450 family 27 subfamily A member 1 ( Cyp27a1 ) and down-regulation of cytochrome P450 family 8 subfamily B member 1 ( Cyp8b1 ), which changes BA biosynthesis from the classical pathway to the alternative pathway

There have been reports of pulmonary aspiration (when food or liquid from the stomach enters the lungs) in people taking GLP-1 medication while undergoing surgery requiring sedation, even when instructed to fast before the surgery

muscle wasting)

They also slow how quickly the stomach empties, so you feel full longer, and they act on appetite signals in the brain to reduce hunger and cravings

Some even show promising signs of treating other illnesses, such as heart disease and alcohol addiction