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Research published in PMC found that participants taking semaglutide lost an estimated 10% or more of their muscle mass during a 68-week treatment period, roughly equivalent to 20 years of age-related muscle loss

Despite these extensive efforts and expenditures, obesity rates continue to climb, as do the associated consequences, contributing to as many as 500,000 preventable deaths every year

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Naltrexone has been studied directly for alcohol use disorder for decades