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Each method employs stable labeled internal standards for quantitation through linear regression analysis, with calibration and QC standards maintaining accuracy within 15% of the nominal value and precision 10%
Rheumatology (Oxford)
LaRowe SD, Myrick H, Hedden S, et al
Market Overview 4.1
However, nearly 50% of patients with HF symptoms have a normal or preserved EF (HFpEF, defined as EF 50%) ( 1.1 Challenges in modeling HFpEF Unlike HFrEF, HF in HFpEF patients usually does not trace back to a primary injury of cardiomyocytes but rather a plethora of extra-cardiac perturbations ( 1.2 Approach to validating HFpEF models Although the complex etiologic and pathophysiologic paths of HFpEF pathogenesis pose a great challenge to the development of pre-clinical models, this process can be aided by a consensus on what HFpEF features the animals should manifest
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