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While certain foods (like yerba mate, fiber, and protein) can naturally stimulate a small rise in GLP-1, they are nowhere near the potency of the pharmaceutical GLP-1 drugs

Some peptides are administered for a defined treatment course, while others are continued long-term for ongoing wellness optimization

The figure below captures this central tension: payers are almost evenly split in their perspectives on treatment of obesity, with some regarding pharmaceutical coverage for obesity as a response to a chronic medical condition, while others see it more as addressing a lifestyle issue

Similarly, sex and race have not been shown to significantly affect drug clearance

The challenge is that not all PCPs prescribe the same way