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Studied for its reduced binding to IGF-binding proteins

It is typically recommended for short-term use only, usually a few weeks to a few months

That left open whether the same mechanism could produce lasting, clinically meaningful weight and body-composition change [1, 3]

Ipamorelin and other growth hormone releasing peptides may also increase hunger, as its function mimics the function of ghrelin, the hunger hormone that increases appetite [13]

For patients primarily seeking weight management, either with or without type 2 diabetes, higher-dose formulations such as semaglutide 2.4 mg (Wegovy) or liraglutide 3 mg (Saxenda) may be more appropriate