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With low platelet counts, the body cant clot as well, causing more bleeding and bruising

Medications know to cause bone marrow suppression (e.g., myelosuppressive antineoplastic agents) may result in a blunted or impeded response to methylcobalamin, vitamin B12 therapy

This is part of why B12 has a strong safety record, and it is also why levels sometimes need regular replenishment during active treatment

Injections may offer different absorption characteristics than oral routes, though the clinical significance is still being studied

Even with a healthy diet, it is not always easy to get the right balance of essential nutrients, especially when you are trying to lose weight