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Kidney and cardiovascular outcomes SURPASS-4 kidney composite HR 0.58, slower eGFR decline (-1.4 vs -3.6 mL/min/1.73m2/yr), UACR -6.8% vs +36.9%
grants No
(2020) published a validated detection assay specific to LongR3-IGF-I, Des(1-3)-IGF-I, and R3-IGF-I in athlete samples
Different peptides act on different receptors, pathways, and biological systems
These mechanisms range from hormone replacement and receptor modulation to direct antimicrobial activity, immune system regulation, and tissue repair processes
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