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J Allergy

Instead, the authors showed that hyperosmotic shock leads to breakdown of sphingomyelin, accumulation of ceramide, and later on to PS exposure and cell shrinkage

Under sepsis stress, damaged type II alveolar epithelial cells release exosomes (Epi-Exos, pink), inducing alveolar macrophages to polarize toward the pro-inflammatory M1 phenotype ( 2 Literature search strategy and selection criteria To systematically construct the multidimensional communication network of exosomes in ARDS and minimize the selection bias inherent in traditional narrative reviews, a comprehensive literature search was conducted