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The cell lysates were treated with 10 mM of TCEP for 30 min and then incubated with 25 mM of NEM for 2 h at room temperature to reduce disulfide bonds and cap the free cysteine residues, respectively
There was a survodutide dose-dependent decrease in bodyweight up to 8.7% with the high-dose survodutide producing greater bodyweight reduction compared to semaglutide [48]
May 2007;38(4):456-9
Furthermore, miR-155 normally promotes macrophage cholesterol efflux and reduces cholesterol ester accumulation by upregulating CEH expression, thereby inhibiting foam cell formation and atherosclerosis development (145)
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