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It is approved only for short-term use (up to 12 weeks), which limits its utility for chronic weight management

Accessed March 20, 2026 at Aronne LJ, Horn DB, le Roux CW, et al

Bedtime injection timing mitigates nausea and flushing by allowing peak side effects (which occur 13 hours post-injection) to coincide with sleep, when they are not consciously perceived

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Anyone experiencing memory problems or cognitive changes should consult their GP for appropriate investigation, which may include cognitive screening, blood tests, and neuroimaging as per NICE guidance (NG97)