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This depletion occurs because acetaminophen metabolism generates a reactive metabolite (NAPQI) that binds glutathione for neutralization and elimination
Effect of acetyl-L-carnitine treatment on brain adenylate cyclase activity in young and aged rats Eur Neuropsychopharmacol 1993
However, several animal and human studies have cast doubt on the effect of G6PD-d on IL-10 secretion
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