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The administration of high doses of lipoic acid by injection to rats decreased the activity of two biotin-dependent enzymes by about 30%-35% (122), but it is not known whether oral or intravenous lipoic acid supplementation substantially increases the requirement for biotin in humans (123)
PubMed laboratory research record [PMID: 7262019] PubMed record related to this compound for laboratory literature review
Nicotinamide N-methyltransferase: a novel therapeutic target
300 Diabetes Insulin resistance and high blood glucose levels increase oxidative stress, trigger vascular inflammation and endothelial dysfunction, activate platelets and pro-coagulation proteins, and inhibit fibrinolysis
The 0.9% benzyl alcohol concentration provides effective antimicrobial protection without compromising peptide stability
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