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TB-500 may support the synovial and subchondral environments surrounding cartilage, improving the overall joint milieu even if direct cartilage effects remain limited

Prolotherapy aims to accelerate the bodys own healing process to repair these connective tissues to strengthen and stabilize the bodys joints and movements without the unwanted side effects of cortisone steroid injections

Vitamin B12 is abundant in most animal products like meat and dairy

Regular B12 injections can help combat fatigue, improve stamina, and support an active lifestyle

doi: 10.3389/fphar.2022.1026182 Received 23 August 2022 Accepted 23 November 2022 Published 14 December 2022 Volume 13 - 2022 Edited by Junmin Zhang, Lanzhou University, China Reviewed by Yurong Lai, Gilead, United States Mei-Hua Qu, Weifang Second Peoples Hospital, China Updates Copyright 2022 He, Feng, Guo, Zhou, Li, Zhang, Zhang, Wang, Wang, Hao, Zhang, Gao, Gu, Zhang, Li and Li