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Growth hormone-releasing hormone analogs, such as tesamorelin, sermorelin, and CJC-1295, stimulate the pituitary to release growth hormone in a pattern closer to natural pulsatile secretion than injected human growth hormone produces
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While they may cause modest increases in heart rate (typically 2-4 beats per minute) and modest decreases in blood pressure, they do not significantly raise core body temperature or substantially accelerate metabolic rate
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