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These shifts frequently accompanied a surge in optimism and confidence
As a reminder, agonists attempt to mimic the molecules action, while antagonists attempt to block the molecules action
About half of the participants received semaglutide while the other half received the placebo
Novo Nordisk also noted that semaglutides safety profile in the ESSENCE trial was consistent with results from previous studies of the GLP-1 agonist
(read about COMT)[ref] Not all studies agree, and some studies show that the MTHFR C677T variant has little to no impact on depression risk
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