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Cutaneous hypersensitivity reaction to dulaglutide: a case report of an allergic reaction

Tirzepatide (Mounjaro, Zepbound) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management and chronic weight management in adults with obesity or overweight with weight-related comorbidities

Cautions for the wider drug class Class-level Approved GLP-1 medicines carry label warnings about pancreas inflammation, gallbladder problems, thyroid tumours seen in rodent studies, and low blood sugar when combined with insulin or sulfonylureas (a diabetes drug group)

They also slow down how fast food leaves the stomach

Since muscle tissue is more metabolically active than adipose tissue (fat), loss of muscle mass leads to a reduced metabolic rate