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Bertelli A, Cerrati A, Giovannini L, Mian M, Spaggiari P, Bertelli AA
Semaglutide works by mimicking the GLP-1 hormone, targeting receptors in the brain involved in appetite regulation
alone, an estimated 1 in 8 adults nearly 12% of the population have reported using medications such as Wegovy (semaglutide) and Zepbound (tirzepatide)
NICE NG28 recommends considering an SGLT2 inhibitor as the preferred option in adults with type 2 diabetes and chronic kidney disease or heart failure, unless contraindicated or not tolerated
Randomized, controlled clinical trials have demonstrated that long-acting GLP-1 RAs are associated with reduced risk of CV outcomes in individuals with T2D and high CV risk in the clinical trial setting [16, 17]
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