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Androgens, whether in excess (Hyperandrogenism) or in deficiency (Hypoandrogenism), cause oxidative stress by affecting immunological responses, fostering chronic inflammation, causing mitochondrial dysfunction, and causing oxidative damage in reproductive organs, thereby affecting fertility and reproductive health ( Table 1 )

Brains were removed, post-fixed in the same fixative for 1 wk, washed 3 times with PBS, and then stored in PBS at 4C

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Intriguingly, ALI dose-dependently suppresses the protein content of Nrf2, HO-1, and GPX4