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For instance, Lim et al
While its naturally present in every cell, its levels decline due to stress, ageing, pollution, and UV exposure
In the beginning, the elderly had 55.2% less glycine and 24.4% less cysteine in their red blood cells
In this study, glutamine flux was directed toward the generation of R-2-HG in IDH1/2 mutant cells, and the kinetics of R-2-HG formation were proportionally of the same order of magnitude as those of glutamate or -KG formation via glutaminolysis
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