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Archived from the original on January 14, 2025

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Patients should be aware of serious adverse effects requiring medical attention, including: severe abdominal pain with or without vomiting (pancreatitis)

A summary of approximate phases, based on trial data, is as follows: Weeks 14: Appetite suppression and early metabolic changes may begin Weeks 412: Noticeable weight loss may commence Weeks 1248+: Progressive weight reduction, continuing through the trial period at higher doses These timelines reflect phase 2 trial experience and may differ in real-world settings

Incidence rate difference (IRD) and hazard ratio (HR) were estimated in the matched cohorts