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Physicians typically recommend GLP-1 therapy in teens only after intensive lifestyle intervention has been attempted and metabolic comorbidities (such as type 2 diabetes or severe hypertension) are present

Abbreviations ROS: Reactive oxygen species RNS: Reactive nitrogen species O 2 : Superoxide radicals OH: Hydroxyl radicals H 2 O 2 : Hydrogen peroxide NO: Nitric oxide ONOO: Peroxynitrite ROS: Reactive oxygen species CVDs: Cardiovascular diseases AD: Alzheimers disease 4-HNE: 4-Hydroxynonenal 8-OHdG: 8-Oxo-hydroxyguanosine MDA: Malondialdehyde PD: Parkinsons disease SOD: Superoxide dismutase RA: Rheumatoid arthritis References Phaniendra A, Jestadi DB, Periyasamy L

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Most people experience mild or no nausea after 46 weeks, especially if they follow dietary adjustments and use a slower dose escalation