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Levels should be in the normal or high-normal range if supplementation is adequate

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This activation significantly increased the Bcl-2-associated X protein (Bax)/B-cell lymphoma 2 (Bcl-2) ratio and cysteine-aspartate protease 3 (Caspase-3) expression, inhibited GPX4 and quinone oxidoreductase 1 (NQO1) expression, increased MDA levels, and promoted apoptosis, ferroptosis, and lipid peroxidation in NSC-34 cells

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Natural extracts and their bioactive compounds have recently gained recognition as potential lead molecules in drug discovery for cancer treatment (159,160)

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