glp-1 birth defects receptor agonists, semaglutide, liraglutide, tirzepatide, are now being prescribed at unprecedented rates to women of reproductive age. Until recently, we had very little data on what periconceptional exposure actually means for glp 1 while trying to

Both compounds are supplied exclusively for research purposes

GLP-1 drugs work to control blood sugar by: Triggering insulin release from your pancreas: Insulin is an essential hormone that enables your body to use your food for energy

This explains why the PKA-inhibitor Rp-cAMPS reduces the relative inhibitory effect of physiological concentrations of GLP-1(7-36) by 50%

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In addition to controlling obesity and type 2 diabetes, two key cardiovascular risk factors, GLP-1RAs may stabilise atherosclerotic plaques, mitigate post-prandial hyperlipidaemia, and reduce sympathetic nervous system activity that contributes to elevated blood pressure