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ALKBH7, AlkB Homolog 7

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[1] Unlike amphetamine abuse, where drug tolerance necessitates escalating doses to achieve the same effect, tolerance to clinically relevant doses of amphetamine plateaus after the initial titration period, and "drug holidays" (i.e., temporary treatment discontinuation) are not required to prevent the development of tolerance

After initial correction, some individuals may require ongoing maintenance injections (often monthly) if they cannot adequately absorb B12 from diet or oral supplements

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