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Later medications like semaglutide and tirzepatide are engineered versions - chemically modified human GLP-1 with structural changes that prevent degradation and extend half-life from seconds to days
However, Venter says that patients get used to injecting themselves in his experience
Users can experience not just nausea and flushing, but also appetite loss, increased libido, and sometimes fatigue
These are the primary ways semaglutide affects the body and how these effects can encourage weight loss
When GLP-1 therapy is appropriate, it may be combined with nutrition, physical activity, cardiovascular risk management, and ongoing medical monitoring as part of a broader health plan
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