Journal of Functional Foods, 100, 105367
Warning Signs to Watch For If you are taking Ozempic, Wegovy, Mounjaro, or any GLP-1 medication, see your dentist promptly if you notice: Your mouth feels consistently dry, even when you are drinking plenty of water

Patients should contact their GP or diabetes specialist nurse if dizziness is: Severe or persistent , significantly impacting daily activities or quality of life Associated with recurrent hypoglycaemia , particularly readings below 4.0 mmol/L or readings below 3.0 mmol/L (level 2 hypoglycaemia) or episodes requiring assistance from others Accompanied by other concerning symptoms such as chest pain, palpitations, severe headache, visual disturbances, slurred speech, or weakness Resulting in falls or near-falls , which pose injury risk, especially in older adults or those with reduced mobility Immediate medical attention (via 999 or attendance at A&E) is required if dizziness occurs alongside: Signs of severe hypoglycaemia with confusion, loss of consciousness, or seizure activity Symptoms suggesting cardiovascular events (severe chest pain, breathlessness, or syncope) Neurological symptoms that might indicate stroke (facial drooping, arm weakness, speech difficulties - remember the FAST acronym) Severe dehydration with inability to retain fluids, reduced urine output, or altered consciousness For urgent but non-life-threatening concerns when unsure what to do, NHS 111 can provide appropriate clinical advice

Summary Keywords organoid, 3D cultures, spheroids, mitochondrial diseases, neurodevelopmental disorders, high-throughput screening, drug repurposing Citation Coronel R, Garca-Moreno E, Siendones E, Barrero MJ, Martnez-Delgado B, Santos-Ocaa C, Liste I and Cascajo-Almenara MV (2024) Brain organoid as a model to study the role of mitochondria in neurodevelopmental disorders: achievements and weaknesses
Tesamorelin, by contrast, primarily reduces visceral fat linked to lipodystrophy and improves metabolic health in individuals with abdominal obesity