Limited clinical data exist supporting L-carnitine's use in the management of mitochondrial dysfunction related to aging and apoptosis, AIDS-related dementia complex, drug-induced anemia, bipolar depression, cachexia, cardiovascular disease, dyslipidemia, dysthymic disorder, fatigue, drug-induced hepatotoxicity, intermittent claudication, migraine prophylaxis, muscle cramps, and drug-induced peripheral neuropathy
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It is also approved for the treatment of moderate-to-severe obstructive sleep apnea in adults with obesity
Impaired glucose metabolism, anti-diabetes medications, and risk of thyroid cancer