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Cascara sagrada is the common name of the California buckthorn (Rhamnus purshianus), a shrub that grows in the Pacific Northwest
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Toxicol Appl Pharmacol 2010
After the injection, you might spot some mild redness or swelling at the injection site, though this should subside within a few hours
The resulting suspension was separated by centrifugation at 12,000 rpm for 30 min at 4 C, and the protein concentrations was performed as in a previous report [28]
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