Discontinuation rates within the first year are consistently reported between approximately 45 and 75% (Sikirica et al., 2017
Hsu TM, Noble EE, Liu CM, Cortella AM, Konanur VR, Suarez AN, et al
Nonsurgical body contouring treatments or breast surgery may provide more balance, shape, and firmness for those with significant breast changes
The most common side effects of tirzepatide are gastrointestinal: Nausea: Reported by 12-33% of participants depending on dose (most common early in treatment) Diarrhea: 12-21% of participants Constipation: 6-11% of participants Vomiting: 5-13% of participants Decreased appetite: Expected therapeutic effect but can be uncomfortable These side effects are typically most intense during the first few weeks at each new dose level and tend to improve as the body adjusts
Ahlborg G, Jensen-Urstad M