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Recent studies show that GLP- 1 function is impaired in people with T2DM, although GLP- 1 secretion is preserved
Cancer , 115 , 741-751, doi: Das, F., Dey, N., Bera, A., Kasinath, B
In the MD studies, weaker interactions of oxyntomodulin with residues deep in the cavity, particularly R190 2.60 , were coupled with a loss of stable interactions along the entire face of the TM2 helix and weaker interactions with ECL2, all of which interact with the same face of the helical GLP-1 peptide (Fig
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