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Fish, meat, and risk of dementia: cohort study

Answer: Epithalon is generally described as well tolerated in the available research, but it is not FDA-approved as a drug, long-term human safety data are limited, and it should only be used under medical supervision

Molecular Metabolism,2019, 30

ESC is rapidly metabolized in phase II reactions, mainly through glucuronidation by UDP-glucuronosyltransferases (especially UGT1A6 and UGT1A9) and sulfation by sulfotransferases (SULTs)