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While some individuals may experience the effects for several weeks, others may find that the benefits wear off sooner

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It has also been suggested that delayed emptying of the lower GI tract in one-half of GERD patients leads to an increase in intragastric pressure, and that a decrease in barrier pressure (the difference between the lower sphincter pressure and the intragastric pressure) is one of the factors contributing to the pathogenesis of GERD (71)

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These amounts can vary based on the research goals and the specific injury being treated