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Human umbilical cord mesenchymal stem cells reduce renal tubular epithelial cell apoptosis by regulating the Wnt/beta-catenin pathway in diabetic nephropathy

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investigated the proximal signaling cascade and found that the mitochondrial phosphatase phosphoglycerate mutase family member 5 (PGAM5) is also involved in various pathways of regulated necrosis via interaction with another mitochondria-related protein dynamin-related protein 1 (Drp1) [213, 214]