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Because riding requires more skill and concentration than driving a four-wheeled vehicle, even relatively low levels of alcohol in the bloodstream (BAC) can be deadly: a rider with a BAC of 0.03 is three times more likely than a sober rider to be involved in a fatal crash

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In diseases characterized by chronic ER stress, such as diabetes and neurodegenerative disorders, modulating the UPR and autophagy could provide therapeutic benefits