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Lixisenatide was largely outcompeted by newer GLP-1s that offer stronger A1C and weight-loss results

If slow-wave time shrinks, you may still sleep, but you can wake up feeling flat

New England Journal of Medicine Why it matters: This isnt just more semaglutide. The goal is synergy pairing GLP-1 with an amylin-based approach to enhance satiety and reduce energy intake

This can lead to a build-up of toxins in the liver and other organs, damage to cells requiring more cellular repair, and the inability of energy production

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