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Supporting a dominant role for diet composition in establishing the Firmicutes : Bacteroidetes ratio, previous work has shown that mice maintained on a high-fat diet had a similar cecal Firmicutes : Bacteroidetes ratio to those maintained on a high-carbohydrate diet 77
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PMID: 39796574 Aguayo-Ceron, K.A., et al
The NRF2-dependent effect was identified through the antioxidative response element in target gene loci, while NRF2-independent effects act through DNA 5hmC modifications via the regulation of the metabolite L2HG
People with primary insomnia show lower activity of a key antioxidant enzyme and higher signs of oxidative stress compared to healthy sleepers
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![PDF] GLP-1 Based Combination Therapy for Obesity and Diabetes](https://figures.semanticscholar.org/73983626886b6439761b6844997806367e881df8/3-Figure1-1.png)
