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IV hydration therapy is commonly used to treat severe dehydration caused by illness, injury, excessive sweating, electrolyte imbalances, and in cases where individuals cannot drink fluids orally due to nausea, vomiting, or dysphagia

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Asp is also the precursor of four essential amino acids (methionine, threonine, lysine, and isoleucine)

Phase 2 dose-finding trial (Lancet 2021) showed clear dose-response from 0.3 mg up to 4.5 mg/week, but 2.4 mg is the dose Novo Nordisk advanced into Phase 3 and is the most commonly self-reported community ceiling

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