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In the face of vitamin B 12 deficiency, conversion of methylmalonyl-CoA to succinyl-CoA cannot take place, which results in accumulation of methylmalonyl-CoA and aberrant fatty acid synthesis
( d ) GSEA analysis of data from ( b, c ) run against metabolic gene sets (defined in 10 )
Dealing with nagging injuries or slow recovery times can be a major roadblock for anyone leading an active life
It therefore has the potential to become a powerful model for studies of basidiomycete biology and fungal pathogenesis mechanisms
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