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GIP and/or GLP-1 receptors are possibly involved in anti-apoptotic effects, synaptic plasticity, memory, reward functions, and emotional responses, which may have a positive impact on a number of neurodegenerative diseases [8]

DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of Alzheimers disease

Treatment for Alzheimers disease: has anything changed

However, they also come with potential drawbacks like allergic responses, risk of low blood sugar (hypoglycemia), and the safety of usage during pregnancy is not well established

Written by Dr Linsey Gani Dr Linsey Gani is an endocrinologist experienced in weight management and metabolic health