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[23] Cyanocobalamin is usually converted to hydroxocobalamin in the serum, whereas hydroxocobalamin is converted to either methylcobalamin or adenosylcobalamin

This means 0.125 mL (12.5 units on an insulin syringe) delivers 0.25 mg (250 mcg)

Rarely, allergic reactions can occur, presenting as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat

Individuals who begin supplementing with B12 early in life can reduce their risk of age-related cognitive decline and improve long-term brain health

In a Danish cohort of patients with inflammatory bowel disease receiving infliximab, infusion reactions were most strongly associated with younger patients and with episodic therapy