Han, Y., Kim, S., Park, T., Hwang, H., Park, S., Kim, J., et al
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Figure 2: Novel Incretin Mimetic Assets for T2DM and Obesity in Phase 2/3 of Development Remaining Unmet Needs Remaining Unmet Needs Though the value proposition of on-market GLP-1 and dual-agonists is strong, several key unmet needs still exist for incretin mimetics across diabetes and obesity, namely: (1) improved efficacy, (2) better tolerability, (3) more convenient options / alternative ROAs, and (4) improved access and affordability
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And certain spices turmeric, cinnamon, cayenne have demonstrated meaningful GLP-1 effects in human studies