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87 , E1E9 (2000)
P7 was known with longstanding bowel problems with significant bloating, nausea, vomiting, and constipation and was found to have a slow gut motility
This differs from standard endocrinology, where treatment generally requires a recognized deficiency, consistent symptoms andwhen necessaryconfirmatory or dynamic testing
Notably, excess hemin exposure exacerbates the disease severity of SCD 19,20 and heme-scavenging strategies such as intravenous infusion of hemopexin are propective 21,22
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