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It also crosses the blood-brain barrier, allowing it to directly detoxify and protect the brain

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The previous reports of multiple beneficial effects of orally administered d-allulose prompted us to infer that it might act through stimulating GLP-1 release and/or vagal afferent signaling, both of which transmit gut signals to remote organs including the brain

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First, as a result of the nature of study design, although associations can be directly assessed, causality requires additional assumptions that the study design attempts to address but may not fully meet