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2 Materials and methods 2.1 Search strategy and study selection The systematic literature review was conducted by searching PubMed , Web of Science, and Scopus databases, considering publications available up to May 2023

It downregulates the expression of cyclin D1, cyclin-dependent kinase (CDK) 4, and CDK6 proteins in a dose-dependent manner, arresting the cell cycle at the G1 phase

It seems to help reduce the activity of tyrosinase, an enzyme that is involved in the synthesis of melanin, leading to a lighter skin tone and diminished dark spots

Scheduling an initial consultation at our clinic is a valuable first step

I launched this movement with my fellow Lyme Warriors in mind, knowing that I am not the only patient who would suffer if these regulations are pushed through