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Store lyophilized material at 4 F (20 C) or below Allow vial to reach room temperature before opening Protect from light, heat, and humidity Use sterile laboratory equipment during preparation Avoid repeated freezethaw cycles Label reconstituted samples with preparation date and concentration Following these practices helps support consistent and reproducible laboratory results

Because a large number of comparisons were performed on the relative abundance data, main effect results from these analyses also underwent a BenjaminiHochberg false discovery rate (FDR) correction for multiple comparisons, and instances where a result was significant after this correction have been duly noted

Regarding plasma B12 - this is not the case, serum B12 often remains highly elevated (well over the normal range) even while symptoms return - this is why testing B12 once treatment begins is not recommended

The companys verified purity through third party testing gives researchers confidence in their results

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