In the Pancreas: GLP-1 stimulates insulin secretion in a blood glucose dependentmanner hence decreasing B cell over function, enhancing Beta-cell survival rate, decreasing B- cell apoptosis and preserving B-Cell mass
it acts as a roborant in cases of stress, overexertion, exhaustion and reduced resistance, and as a tonic in cases of weakness, secondary anaemia and chilling
Circulation 150(16):12881298 Neeland IJ, Linge J, Birkenfeld AL (2024) Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies
These are real findings, but "increased GLP-1 after a meal" is not the same as "sustained GLP-1 receptor activation at therapeutic levels." Fiber supports gut health and may modestly improve satiety
This is thought to explain its greater efficacy compared to semaglutide alone