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One way this is done is through conjugation with GST (glutathione S-transferase) enzymes

After this period, injections can be administered once per month, which this frequency is enough to reverse the signs of vitamin B12 deficiency

Many practitioners recommend supplementing with oral methylcobalamin or sublingual B12 in addition to the compound, particularly for patients who have been on therapy for more than six months or who have documented low B12 levels

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