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Clin Exp Hypertens

In: Aboubakr S, Abu-Ghosh A, Acharya A, Adibi Sedeh P, Aeby T, Aeddula N, et al

Cagrilintide addresses this limitation directly: through chemical modifications to the amylin molecule, Novo Nordisks scientists created a compound with a half-life of approximately seven days long enough for once-weekly dosing

Key readouts include: TRIUMPH-1 (obesity): Participants on the 12 mg weekly dose achieved an average body-weight reduction of roughly 28.3% at 80 weeks and up to 30.3% at 104 weeks , figures that approach outcomes previously associated only with bariatric surgery

This has led to ongoing research into whether the delay in gastric emptying is always temporary or if it can become a long-term issue for certain sensitive individuals